WHAT ARE THE PHASES OF CELLULITE?
Adipose tissue develops slowly towards cellulite in several phases.
-Interstitial oedema: due to increased intracapillary pressure there is an increase of capillary permeability that leads to leakage of liquids and proteins of high molecular weight into the connective tissue. This excess permeability and the interstitial flooding originate a lymphatic overload with development of oedema. Intracapillary hyperpressure is responsible for the fragility of vascular walls causing perturbing changes. The release of aggressive substances such as histamine, serotonin and prostaglandins triggers tissue reactions of an inflammatory type.
-If excess protein is not depolymerised by macrophages there is fibroblastic stimulation that triggers the formation of a fibrin wall that surrounds adipocytes. These adipocytes are hypertrophied because they cannot undergo metabolic interchanges adequately with an oedematized intersticium embedded in toxins. First, micronodes are formed, later becoming macronodes enclosed in conjunctive fibres identified upon palpation.
-The sclerosis phase is the last phase with maximum fibrosis that usually comprises nerve endings making cellulite painful and closing a vicious circle of vascular and tissue decompensation.
-In this way, in the presence of the same factors, these same factors manifest differently in women and in men.